Kowanin, Suatu Santon dari Kulit Batang Garcinia cowa Roxb

Darwati ', Husen H Bahti, Supriyatna ', Dachriyanus '

Abstract


The compound tetraoxygenated xanthone was isolated from the crude extract of the stem bark of Garcinia cowaRoxb. The compound tetraoxygenated xanthone was caried out as yellow crystal with melting point 136-1370C.The structure of this compound was detremined base on spectroscopic methods, including UV, IR, 1H-NMR,13C-NMR 1D and 2D. The compound was found to exhibit cytotoxicity against T47D cell by SRB method

Keywords


cowanin, tetraoxygenated xanthone, Garcinia cowa Roxb., T47D, SRB

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References


Burkill, I.H. 1966. Tree Flora of Malaya, Manual for Foresters Vol. 1 (A-H). Malaysia, Kulalumpur: Ministry of Agriculture and Cooperatives

Heyne, K. 1987. Tumbuhan Berguna Indonesia. Jilid III. Jakarta: Yayasan SaranaWana Jaya.

Mahabusarakum, W., Chairerk, P. & Taylor, W.C.. 2005. Structure elucidation of xanthones from Garcinia cowa Roxb. Late, Phytochemistry: 66, 1148-1153.

Na Pattalung, P., Thongtheeraparp, W., Wiriyachitra , P. & Taylor, W.C. 1994. Xanthones of Garcinia cowa. Planta Med. 60: 365-368.

Kanda Panthong , Wipapan Pongcharoen, souwalak Phongpaichir & W.C. Taylor. 2006. Tetra oxygenated xanthones from the fruit of Garcinia cowa. Phytochemistry 67: 999-1004.

Justin Komguem , A.L. Meli, R.N. Manfouo, David Lontsi, F.N. Ngounou, V. Kuete, Hippolyte W. kamdem, Pirre Tane, Bonaventure T. Ngadjui, Beiben L. Sondengam & Joseph D. Connolly. 2005. Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activity, Phytochemistry 66: 1717-1773.

Panthong, K, Pongcharoen, W., Phongpaichit, W. & Taylor, W.C. 2006. Tetraoxygenated Xanthones from The Fruit of Garcinia cowa. Phytochemistry 67: 999-1004.

Poomipamorn, S. & Kumomg, A. 1997. Edible Multiporpuse ree Species Faung Fa. Bangkok: Printing (in Tai).

Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahon, J., Vistica, D., Warren, J.T., Bokesch, H., Kenney, S. & Boyd, M.R. 1990. New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening. Journal of the National Cancer Insitute 82: 1107-1112.

Wahyuni, F.S., Lajis, N.H., Stanslas., J., Ali, D.A.I., Shaari, K. & Dachriyanus. 2004. Isolation of bioactive compounds from Garcinia cowa Roxb. 14th Indonesian National Symposium on Natural Products Chemistry. Bandung,16- 17th December 2004.




DOI: http://dx.doi.org/10.31258/jni.11.02.%25p

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