PENENTUAN KONSENTRASI GLUKOSA DAN INSULIN DARAH NORMAL DENGAN METODE SIMULINK

Abstract

A study was conducted with the aim of comparing normal glucose concentrations between modeling
results and the experimental results of 6 normal glucose patients. The patterns of graphs produced in
each of the normal glucose patients vary although each patient is treated equally. The results showed
that the modeling is suitable for experimental data in 17-20 year old women who obtained static
glucose concentration of 73 mg / dl. It can be seen that there are several values of transport rate
constant (K) of the same curve fitting value, that is, on glucose flux (Fg) 80000 mg/dl.s parameter,
transport rate of first order (K1) 24.7 s-1, Renal elimination transport rate (K2) 72 s-1, transport rate of
insulin-glucose (K3) reduction 13,9 s-1, pancreas metabolism transport rate constant (K4) 14,3 s-1.
The existence of several parameters that have the same value between modeling and also this
experiment means that the patient in maintaining the balance of blood plasma glucose in the same
daily, blood plasma glucose is balanced when the efficient pancreatic and kidney organs.