Aktivitas Antijamur Air Perasan Daun Seledri (Apium graveolens L.) Terhadap Candida albicans Secara In Vitro

Abstract

Celery (Apium graveolens L.) has been known as traditional medicine. Apigenin is one of active component in Celery
leaf that has fungicidal activity, so celery leaf’s extortion suspected has fungicidal activity to Candida albicans. Apigenin
can solved in water. The aim of this research was to know antifungal activity of celery leaf’s extortion againsts Candida
albicans in vitro.
This is a laboratory experimental research by using completely randomized design and disc diffusion method. Celery
leaf’s extortion was divided into 3 concentrations, there were 25%, 50% and 100%. Ketoconazole 2% was used as
positive control and aquadest as negative control. The result of this research was based on analysis of variance, there
was significant difference between minimal 2 treatment (p=0.000) and confirmed with Post Hoc test, there were significant
difference in all treatments. As the conclusion, celery leaf’s extortion had antifungal activity againsts Candida albicans
in vitro with the best concentration 50% but smaller than ketoconazole 2%.