Isolasi dan Uji Aktifitas Antimikroba Ekstrak Metanol Bunga,Batang dan Daun Sapu Jagad (Isotoma Longiflora (L) Presl.)Terhadap Staphylococcus Aureus

Abstract

Sapu jagad plant (Isotoma longiflora (L) presl.) has been used as traditional medicine in Indonesia to cure severaldisease. Research studies showed this plant contain alkaloid, terpenoid and phenol, but pharmacological effects of thisplant needs further studies. The aim of this research study was to isolate and to determine antimicrobial activity fromthe flower, leaf and bar of methanol extract of Isotoma longiflora (L)presl against Staphylococcus aureus bacteria.The result showed that all extract had antimicrobial activity at 10% b/v concentration. Isolation and fractionationshowed 9 fractions with F2 and F4 were crystallized powder. The result from fractionation showed positive antimicrobialeffect of F1, F2 an F6 at 10% b/v concentration.